|
Non-fluorescent modifications |
||
|
Type of modification |
Price per insertion, |
Price per insertion, |
|
Degenerated bases |
$0.00 |
$0.00 |
|
Degenerated bases |
US$3 / CAN$3 |
US$9 / CAN$9 |
|
2'-O-Me RNA |
US$6 / CAN$6 |
US$12 / CAN$12 |
|
5' Acrydite |
US$60 / CAN$60 |
US$180 / CAN$180 |
|
Inosine (deoxyinosine, dI) |
US$6.67 / CAN$6.67 |
US$16 / CAN$16 |
|
Uridine (deoxyuridine, dU) |
US$6.67 / CAN$6.67 |
US$16 / CAN$16 |
|
5' Phosphorylation |
US$20 / CAN$20 |
US$40 / CAN$40 |
|
3' Phosphorylation |
US$15 / CAN$15 |
US$30 / CAN$30 |
|
5' Amine |
US$14 /CAN$14 |
US$28 / CAN$28 |
|
3' Amine |
US$15 / CAN$15 |
US$30 / CAN$30 |
|
5' Thiol |
US$40 / CAN$40 |
US$80 / CAN$80 |
|
3' Thiol |
US$25 / CAN$25 |
US$50 / CAN$50 |
|
5' Biotin |
US$29 / CAN$29 |
US$78 / CAN$78 |
|
3' Biotin |
US$25 / CAN$25 |
US$50 / CAN$50 |
|
5' Cholesterol 1 insertion/order 2 insertions/order 3 or more insertions/order |
US$200 / CAN$200 US$110 / CAN$110 US$80 / CAN$80 |
US$400 / CAN$400 US$220 / CAN$220 US$160 / CAN$160 |
|
3' Cholesterol |
US$70 / CAN$70 |
US$140 / CAN$140 |
|
5' Digoxigenin |
US$120 / CAN$120 |
US$240 / CAN$240 |
|
3' Digoxigenin |
US$120 / CAN$120 |
US$240 / CAN$240 |
|
Type of modification |
Price per insertion, |
Price per insertion, |
|
5' Fluorescein |
US$24 / CAN$24 |
US$50 / CAN$50 |
|
3' Fluorescein |
US$25 / CAN$25 |
US$50 / CAN$50 |
|
5'-end 6-FAM, HEX or TET |
US$29 / CAN$29 |
US$75 / CAN$75 |
|
3'-end 6-FAM, HEX or TET |
US$49 / CAN$49 |
US$149 / CAN$149 |
|
5' VIC-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' VIC-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' NED-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' NED-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' PET-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' PET-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' LIZ-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' LIZ-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' JOE-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' JOE-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' ROX-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' ROX-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' BHQ-1(black hole
quencher) |
US$50 / CAN$50 |
US$100 / CAN$100 |
|
3' BHQ-2 |
US$50 / CAN$50 |
US$100 / CAN$100 |
|
3' BHQ-3 |
US$50 / CAN$50 |
US$100 / CAN$100 |
|
3' Dabcyl |
US$49 / CAN$49 |
US$99 / CAN$99 |
|
5' TAMRA |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' TAMRA |
US$49 / CAN$49 |
US$149 / CAN$149 |
|
5' Rhodamine |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' Rhodamine |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
5' Rhodamine Green (may replace Oregon Green 514, or Alexa Fluor 500) |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' Rhodamine Green (may replace Oregon Green 514, or Alexa Fluor 500) |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
5' Rhodamine Red |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' Rhodamine Red |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' Eclipse |
US$70 / CAN$70 |
US$199 / CAN$199 |
|
5' Cy3 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' Cy3 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Cy3.5 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' Cy3.5 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Cy5 dye (may replace D4, LC Red 670) |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' Cy5 dye (may replace D4, LC Red 670) |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Cy5.5 dye (may replace IRD 700, D3 and LC-Red 705) |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' Cy5.5 dye (may replace IRD 700, D3 and LC-Red 705) |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Cy7 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' Cy7 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Cy7.5 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' Cy7.5 dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Texas Red (may replace PET, ROX, Cy3.5, Redmond Red, LC Red 610) |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' Texas Red (may replace PET, ROX, Cy3.5, Redmond Red, LC Red 610) |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Cal Fluor Red 610 (may replace Texas Red, PET, ROX or Cy3.5) |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
5' Cal Fluor Red 635 (may replace LC-Red 640) |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' LC Red 610 replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' LC Red 610 replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' LC Red 640 replacement dye |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' LC Red 640 replacement dye |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
5' LC Red 670 replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' LC Red 670 replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' LC Red 705 replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' LC Red 705 replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' IRD 700-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' IRD 700-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' IRD 800-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' IRD 800-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' WellRed D2-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' WellRed D2-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' WellRed D3-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' WellRed D3-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' WellRed D4-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
3' WellRed D4-replacement dye |
US$29 / CAN$29 |
US$150 / CAN$150 |
|
5' Yakima Yellow |
US$120 / CAN$120 |
US$300 / CAN$300 |
|
3' Yakima Yellow |
US$80 / CAN$80 |
US$140 / CAN$140 |
|
5' Alexa Fluor 350-replacement |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' Alexa Fluor 350-replacement |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
5' Pacific Blue-replacement |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' Pacific Blue |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
5' Redmond Red (may replace TxRed, PET, ROX or Cy3.5) |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
3' Redmond Red (may replace TxRed, PET, ROX or Cy3.5) |
US$80 / CAN$80 |
US$240 / CAN$240 |
|
Other modifications (such as |
Please inquire |
Please inquire |
|
Discounts for more
than
|
Please inquire |
Please inquire |
The 200 nmole (0.2 micromole) synthesis
scale would typically yield 0.1-0.2 micromole (100-200 nmole) final
product. Guaranteed minimum 50 nmole (shorter oligos) or 12 OD units (longer oligos), desalted, non-modified oligos,
ordered at the 200 nmole synthesis scale. Standard purity
includes free desalting. Modified and additionally purified oligos may have lower
yields. All oligos are quantified and three different units of measure
are provided to the customer. The exact relation between these three
units is calculated by a computer for each oligo; as a very rough approximation
for a 20 base long oligo, 100 nmole equals approx. 20 OD260 units, or 600
micrograms. Example of price calculation for one oligonucleotide, 20-mer,
100 nmole scale, 5'-end labeled with 6-FAM: 20 x 0.29 = 5.80 basic price
of the oligo, plus 29.00 for the 6-FAM, total = 34.80 USD.
Phosphorothioated oligonucleotides (PTO)
|
Synthesis
scale |
Additional
charge per PTO base |
Basic
cost per base |
Setup
charge |
|
0.2
μmole |
US$1.50
/ CAN$1.50 per PTO base |
US$0.39 / CAN$0.39 |
$0.00 |
|
1.0
μmole |
US$1.50
/ CAN$1.50 per PTO base |
US$0.79 / CAN$0.79 |
$0.00 |
|
15
μmole |
US$10.00
/ CAN$10.00 per PTO base |
US$6.50
/ CAN$6.50 |
US$30
/ CAN$30 |
Example:
One oligo of 20 bases at the 200 nmole scale, of which 3 backbone links at each end are
phosphorothioated: 20 x 0.39 = 7.80, plus (3+3) x 1.50 = 9.00, for the
total of 16.80.
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1997-2013 Alpha DNA